Labconco FreeZone Triad 7940010 Series, User Manual

Page 1: ...Original instructions FreeZone Triad Freeze Dryers Models 7940010 Series...

Page 2: ...the hours of 7 30 a m and 5 30 p m Central Standard Time Part 7343300 Rev A ECO L423 Warranty Labconco Corporation provides a warranty to the original buyer for the repair or replacement of parts and...

Page 3: ...Your Freeze Dryer 8 Freeze Dryer Components 9 Setting Up Your Freeze Dryer 9 Component Identification 10 Vacuum Pump Connection 11 Electrical Connection 12 Chemical Resistance of Freeze Dryer Compone...

Page 4: ...cuum Pump Ballast Setting 33 Sample Freezing 33 Shelf Loading 34 Setting the Operating Vacuum Level 34 Freeze Drying Inside the Chamber 36 Manual Mode with Pre Frozen Samples 36 Manual Mode with Unfro...

Page 5: ...ves 48 System Components Collector Chamber Isolation 50 Refrigeration Module Operation 52 APPENDIX A FREEZE DRYER COMPONENTS 53 APPENDIX B FREEZE DRYER DIMENSIONS 55 APPENDIX C FREEZE DRYER SPECIFICAT...

Page 6: ...sensitive Other than food processing e g coffee whole dinners freeze drying has been extensively used in the development of pharmaceuticals e g antibiotics and preservation of biologicals e g protein...

Page 7: ...s is based on the fact that the heat of sublimation is usually absorbed on one side of the frozen sample and must travel through the frozen layer to vaporize water at the other surface In addition as...

Page 8: ...lume of a sample that can be freeze dried at one time is related to factors discussed previously and the size and design of the freeze dry system With any given instrument the capacity is based on the...

Page 9: ...intenance and making minor modifications to your Freeze Dryer are also included Chapter 1 Introduction provides a brief overview of the Freeze Dryer explains the organization of the manual and defines...

Page 10: ...e g Chapter 3 Getting Started Steps required to perform a task are presented in a numbered format Comments located in the margins provide suggestions reminders and references Critical information is...

Page 11: ...read this chapter to learn Electrical supply requirements Vacuum pump requirements Refer to Appendix C Freeze Dryer Specifications for complete Freeze Dryer electrical and environmental conditions spe...

Page 12: ...uring operation could adversely affect performance The Triad Freeze Dryer must be placed on a work surface or table that will support over 400 lbs Refer to Appendix B Freeze Dryer Dimensions for dimen...

Page 13: ...81 Kg The carton allows for lifting with a mechanical lift truck or hand truck If you must lift the Freeze Dryer manually use at least two 4 persons and follow safe lifting guidelines Unpacking Your F...

Page 14: ...RYER Freeze Dryer Components Verify that the components listed below are present and undamaged Qty Part Description Comments 1 1089005 User s Manual USB Flash Drive 1 Various Power Cord See parts list...

Page 15: ...um Release Backfill Port On Standby Button LED Indicator DRAWN BY CHECKED BY DATE DATE PART NAME TOLERANCES UNLESS OTHERWISE SPECIFIED ANGULAR 1 2 DEG INSIDE BEND RAD 1 16 XX 03 XXX 010 REMOVE BURRS A...

Page 16: ...and outlet ports 3 Some vacuum pumps have inlet fittings that clamp to the pump Place the centering ring with filter screen on the inlet fitting 4 Place the hose barb fitting on top of the centering...

Page 17: ...CONJUNCTION WITH THE EXHAUST FILTER TO RETURN TRAPPED OIL BACK TO THE VACUUM PUMP Electrical Connection Make sure that the outlet that you intend to use meets the voltage and amperage requirements lis...

Page 18: ...ffect on any of the materials of construction When using compounds in the Freeze Dryer that are hostile to the materials of construction it is imperative the equipment is thoroughly cleaned after use...

Page 19: ...ution and keep sources of ignition away from the solvents When using flammable or hazardous solvents the vacuum pump must be vented to or operated inside a fume hood Hazardous materials such as strong...

Page 20: ...detailed in Chapter 3 Getting Started read this chapter to learn how to Operate the controls Understand the display Do not use the Freeze Dryer in a manner not specified by the manufacturer refer to A...

Page 21: ...ressing this button will illuminate the display Note the display can also be brought out of low power mode by touching any location on the screen 3 On Standby LED Indicator Blue LED indicator light to...

Page 22: ...Logging 4 Settings 5 Sensors 6 Empty 7 End Point Detection 8 Help Moving between Menu Screens You can move between menu screens by either touching the menu icons or swiping across the screen from lef...

Page 23: ...The value displayed will be RED if the vacuum is 1 500 mbar The value displayed will be GREEN if the vacuum is 1 500 mbar SHELF SAMPLE TEMPERATURE MEASUREMENT Displays the shelf sample temperatures i...

Page 24: ...nly be used for pre freezing samples not for freeze drying since the collector coil is not being cooled in this mode o In Flask This setting is used to freeze dry pre frozen samples when using ONLY th...

Page 25: ...to a two digit sequential number starting with Program 01 that will be incremented as new programs are added to the list i e Program 02 Program 03 The default name can be edited as desired in the New...

Page 26: ...program Pressing the remove button will delete the selected step from the program Changes will not be saved until the Save button is pressed Pressing the Back button will return to the Programs screen...

Page 27: ...ime This time represents how long the system will hold at the Shelf Temp that has been programmed for each Step The time can be set from 00 01 to 99 59 1 min to 99 hrs 59 min It can also be set to an...

Page 28: ...e can be edited as desired in the New or Data View screen Data View Use this button to view the data from a saved data log file in table format Chart Use this button to view data from a saved data log...

Page 29: ...ynchronization data to the Freeze Dryer via the Ethernet connection Daylight Savings ON OFF This feature can be used to adjust the time for areas observing Daylight Savings Time DST 3 Units Select you...

Page 30: ...enter the security code to gain access to each individual screen that has been selected box checked 5 Alerts If a valid network connection has been established via the Settings Network screen and Emai...

Page 31: ...h field to make sure each entry is valid If one or more invalid entries are found the following message will appear EMAIL SETTINGS ERROR Error connecting to email server check your settings If all the...

Page 32: ...g on model The LOW Line Voltage Offset can be adjusted from 0 to 10V 115V models or 0 to 20V 230V models The HIGH Line Voltage Offset can be adjusted from 0 to 10V 115V models or 0 to 20V 230V models...

Page 33: ...res red blue sheath with a brown outer casing They are located inside the housing of the Freeze Dryer and can be accessed by removing the back panel A thermocouple meter can be used to read the thermo...

Page 34: ...ed ON there will be an audible sound each time the display is touched Pressing the Touch Sounds button will toggle between ON OFF Screen Timeout Function If this function is turned ON the screen will...

Page 35: ...nstalled on the Freeze Dryer and any attached accessory The Sensors screen is for viewing only there are no selectable fields on this screen End Point Detection Screen If the communication cable is NO...

Page 36: ...End Point Detection alert is achieved for any given flask Offset from Ref Vacuum This allows the user to determine the level of dryness at which the system will declare that the primary drying end poi...

Page 37: ...tics This screen will give information about the power supply to the Freeze Dryer Voltage Current Frequency and allow the user to run Manual or Auto Diagnostics on the unit User s Manual Go to www lab...

Page 38: ...r gasket 4 Check that each sample valve is closed or in the vent position See Figure 4 Vacuum Pump Ballast Setting Most vacuum pumps are equipped with a gas ballast mechanism The freeze dry process re...

Page 39: ...sired for more complex pre freezing annealing processes then program the vacuum set point to OFF for each of the pre freezing annealing steps If desired place the sample probe in a sample vial to moni...

Page 40: ...rs that must be considered are whether the sample is freeze dried on heated shelves or in glassware attached to sample valves the volatility of the sample itself the size of the sample and the heat en...

Page 41: ...begin ramping the shelf temperature until the set point temperature is achieved After reaching the set point temperature the system will hold at this temperature indefinitely 4 When the collector temp...

Page 42: ...he entered set point value or approx 75 C in Max Cold mode Note With the system starting at room temperature it will take approximately 6 hours to freeze a 2 liter tray of water in Max Cold mode 5 Whe...

Page 43: ...while the sample is pre freezing THE VACUUM SHOULD ALWAYS BE TURNED OFF WHILE USING THE SHELVES TO FREEZE SAMPLES 4 With the desired program selected from the list press the START button 5 The refrige...

Page 44: ...cedure should be followed when using the sample valves to freeze dry 1 Go to the Home screen and press MANUAL then select In Flask 2 Once the collector temperature is less than 80 C and vacuum is less...

Page 45: ...ates the diaphragm Opening the Vacuum Release Control also deflates the stoppering diaphragm The Stoppering Control should be left in the RAISE position when not stoppering The stoppering mechanism is...

Page 46: ...and neutralization after defrost or physical damage to the collector chamber and coil will result Do not attempt to chip ice from the collector coil as damage may occur Never attempt to start the vac...

Page 47: ...a total of 1000 operating hours an alert will be activated It may be necessary to service the vacuum pump more frequently than every 1000 hours depending on the operation of the Freeze Dryer The pump...

Page 48: ...t messages from the Settings Alerts Select Alerts screen Copy Export a Data Log File Data Log Files can be copied exported to a USB flash drive via the USB port on the left side of the Freeze Dryer Th...

Page 49: ...files that are stored on the Freeze Dryer 7 Single click on a file name from the list to download the file 8 Single click on the downloaded file to open the file in Excel Copy a Program If you wish to...

Page 50: ...ng normal operation of the equipment Routine Maintenance Schedule Under normal operation the Freeze Dryer requires little maintenance The following maintenance schedule is recommended As needed 1 The...

Page 51: ...1 The rubber components on the freeze dry system may eventually deteriorate and require replacement The effective life of rubber parts depends upon both their usage and the surrounding environment Che...

Page 52: ...ck the electrical connection of the vacuum pump to the Freeze Dryer If the vacuum pump has a power switch make sure that it is turned on Note If the vacuum pump is plugged directly into a wall outlet...

Page 53: ...all sample valves on the side of the cabinet and ensure all valves are closed or in the vent position 2 Check all vacuum tubing for signs of deterioration or cracking 3 Check all connections and make...

Page 54: ...the two valves on the front c Remove the lower front panel d Remove the one screw on the left side of the control panel e Remove the three screws attaching the right panel to the base and remove the...

Page 55: ...the fluid circulation valve 4 Attach a flexible tube to the exposed port service port The port is 3 8 x 45 male flare 5 Remove the fluid reservoir cap and place the opposite end of the tubing into the...

Page 56: ...tubing by pass 11 Remove the tubing Replace the caps on the valve and replace insulation and covers Replace the cap on the tank 12 Replace insulation and seal air tight Replace rear cover Heat Transfe...

Page 57: ...dical attention Skin Contact Wash contaminated areas with soap and water Remove contaminated clothing and footwear Wash clothing before reuse Discard footwear which cannot be decontaminated Medical at...

Page 58: ...8 53 Original instructions APPENDIX A FREEZE DRYER COMPONENTS The following pages list components that are available for your Freeze Dryer The parts shown are the most common replacement parts If othe...

Page 59: ...es Gasket 6 7365800 2 Temperature Sensor Sample 7 7515302 1 Temperature Sensor Collector Not Shown 8 7337600 1 Control Assembly 9 7840000 1 Gal Heat Transfer Fluid Not Shown 10 1338002 1 Power Cord 23...

Page 60: ...Serum Bottle Capacity of the Triad Freeze Dry System Size Labconco No 100 pcs Shelf Capacity 2 ml 7575010 400 3 ml 7575210 441 5 ml 7573010 233 10 ml 7573210 196 20 ml 7573410 121 30 ml 7573610 86 50...

Page 61: ...formation about the Freeze Dryer including electrical specifications and operating conditions Electrical Specifications Voltage Frequency Amps Catalog Description Nominal Operating Range Hz Max with V...

Page 62: ...ain supply voltage fluctuations not to exceed 10 of the nominal voltage Transient overvoltages according to Installation Categories II Overvoltage Categories per IEC 1010 Temporary voltage spikes on t...

Page 63: ...58 Original instructions APPENDIX D FREEZE DRYER ACCESSORIES Labconco offers a full line of accessories to enhance your Freeze Dryer s operation and usability For a complete list of these accessories...