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MEA Signal Generator:

 The 60-, 120- or 256MEA Signal Generator is used for setting up an experiment with 

sample data for training, controlling, and troubleshooting purposes. Please insert the signal generator (orientation: 

you can read the “ON” and “1   2” on the switch) and test your system with this artificial data and make yourself 

comfortable with the software settings before starting an experiment with biological samples.

You can find the instructions for the signal generators in its bag, on the provided USB stick (Manuals/MEA_Signal_
Generator_Manual.pdf) or online at www.multichannelsystems.com/downloads/documentation.
When working with biological samples, please insert the MEAs in correct orientation.

Important:

 MEAs are not symmetrical! Standard MEAs with one big internal reference 

electrode should be placed with the reference electrode to the left side in the headstage. 
Otherwise, the MEA layout will not match with the pin layout of the channel map in the 
data acquisition programs from MCS. For the orientation of special MEAs, please read 

the respective datasheet. You can find instructions for the handling of the MEAs on the 
provided USB stick (Manuals/MEA_Manual.pdf) or online. Datasheets for each MEA type 
are available online at www.multichannelsystems.com/products/microelectrode-arrays.

• 

Setting up a MEA2100-System

• 

For more information:

•  Manuals on the provided USB stick 
•  www.multichannelsystems.com/

 

downloads/documentation

MEA2100-System: Installation Guide

© 2018
Multi Channel Systems MCS GmbH

Product information is subject to change without notice. 
Products that are referred to in this document may be 

either trademarks and/or registered trademarks of the 
respective owners. The publisher and the author make no 
claim to these trademarks.

Multi Channel Systems
MCS GmbH

Aspenhaustraße 21
72770 Reutlingen
Germany

Phone   +49-7121-909 25 25
Fax        +49-7121-909 25 11

support@multichannelsystems.com
www.multichannelsystems.com

In Case You Experience any Problems

1. 

Consult the manuals provided on the included USB stick or online 

 

at

 www.multichannelsystems.com/downloads/documentation.

2. 

If you do not find help in the manuals, please do not hesitate 

 

to contact our support team via:

 

 

- Email: support@multichannelsystems.com 

 

- Our support form at  

        http://www.multichannelsystems.com/service/support.

3. 

In order to keep your software up-to-date and stay tuned to all 

 

MCS news, please subscribe to our newsletter via our web site 

(“Subscribe Newsletter”).

We hope that your setup was successful and you can now start your 
experiments.

We wish you great progress with your research and are happy to help 
you with any further questions!

Your MCS team

Test of the System and Preparation for Experiment

7

60MEA-SG

120MEA-SG

6

1.  Connect the PPS2 with the power supply 

unit to the power outlet. 

2. 

Connect the PPS2 with the USB cable A-B 

to the computer for PPS2 software control 

(possible via an USB hub).

3.  Connect the tubes of the PPS2 to the 

perfusion solution, the PH01, the perfusion 
out and the waste bottle. Please follow the 

instructions on the leaflet in the tube bag. 
Adjust the flow rate.

Power Supply 

Unit

USB 2.0 Cable A-B

PPS2 Rear Panel

Perfusion In

(via PH01)

Perfusion Out (from MEA)
     Waste Bottle

Perfusion Solution

Connection of the Peristaltic Perfusion System PPS2

Power Outlet

USB 2.0 Port

256MEA-SG

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