NuvaWave Handheld Disinfection Device Instructions for Use
037-0110 (Rev C)
© 2020 UV Innovators, LLC
Page 16 of 35
D in humans. In another mechanism of action, cellular activation by photonic interaction can cause
these cells to produce reactive oxygen species that can attack bacteria and destroy their membranes.
2
UVC acts in a direct mechanism with the DNA of mammalian cells. The UVC energy is absorbed by the
cells and causes a disruption of the thymine dimers of the DNA sequence and the RNA of viruses. This
disruption renders the cells to be unable to replicate or reproduce.
3
This effectively restricts and
causes the cells to die making the UVC wavelength very efficient at pathogen reduction. For this
reason, UVC is known as the germicidal irradiation wavelength.
2.3
H
OW TO
P
ROTECT
Y
OURSELF FROM
D
ETRIMENTAL
UVC
RADIATION
E
XPOSURE
Since the UVC wavelength of light can disrupt the DNA of cells, it is a requirement to protect humans
from this powerful wavelength. The lens of the human eye absorbs most of UVA light, which can cause
cataracts; the shorter wavelengths (UVB & UVC) are absorbed by the cornea, causing potential
damage to these tissues.
4
This is why UV protective eyewear should always be used around UV light. In
addition, the user should wear a NuvaWave face shield (or equivalent UVC certified face shield) to
protect both the eyes and the other exposed skin of the face during the use of products with UVC
irradiation. Most optically transparent polymer materials, like polycarbonate, will block shorter
wavelengths (UVC) and allow visible light to move through. In addition, users of UVC irradiation
devices should protect any exposed skin from direct or indirect exposure to these harmful wavelengths.
Personal Protective Equipment (PPE) is required during disinfection of infected areas. Examples of
PPE are:
Gloves
Gown
Sleeve covers
Goggles/Glasses
Hood
Respirator
Face shield
Boot covers
Face Mask
The minimum required for PPE during the use of NuvaWave is a NuvaWave face shield, gloves, tight
weave long sleeve shirt, tight weave pants, and closed-toe shoes.
2.4
PPE
I
NCLUDED IN THE
K
IT
The Kit provides 2 PPE face shields. Users should always follow the procedures of the facility where
they are working to ensure all PPE options are utilized properly. In addition to the provided NuvaWave
face shield, the user must cover any exposed skin with clothing such as tight weave long sleeve shirt
and pants, gloves, and closed-toe shoes.
2
Hamblin, Michael R., Photodynamic inactivation of microbial pathogens, RSC publishing, 2001, pg. 57-63
3
Yin R, et al. Light based anti-infectives: ultraviolet C irradiation, photodynamic therapy, blue light, and beyond. Curr Opin
Pharmacol 2013; 13(5):731
–62.
4
Sliney, David H., How light reaches the eye and its components, International Journal of Toxicology, 21:501-509, 2002.
