ProStar 335 Photodiode Array Detector
107
Troubleshooting
Excessive noise and/or drift
Excessive noise and/or drift has two primary sources:
A contaminated or leaking flowcell
A worn out lamp
To determine the source of the noise and/or drift:
1. Pump HPLC grade water through the flowcell at 250
µ
L/min
directly from the pump with no column in the system.
2. Set the detector wavelength to 240 nm and a response time
of 2 seconds.
3. Use the ProStar 335 PolyVerify application to perform
diagnostic tests to determine the source of the problem. For
information on using the ProStar 335 PolyVerify application,
refer to the online help.
If the flowcell is the problem, clean it using the procedure given
on page 90. If the cleaning procedure does not rectify the
problem, it will be necessary to replace the flowcell assembly
(refer to page 68). If the lamp is the problem source, it must be
replaced with a new lamp (refer to page 92).
