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FOLD

User’s Manual

HANDBOOK

OF

ADVERSE

DRUG

INTERACTIONS

R

x

The Medical Letter

DIGITAL BOOK

F

IC-168

Electronic Publishers

For Use with the Franklin

Digital Book System

Electronic Publishers

Summary of Contents for IC-168

Page 1: ...FOLD User s Manual HANDBOOK OF ADVERSE DRUG INTERACTIONS Rx The Medical Letter DIGITAL BOOK F IC 168 Electronic Publishers For Use with the Franklin Digital Book System Electronic Publishers ...

Page 2: ... of the DIGITAL BOOK or of the data stored therein whether in electronic or print format Such copying would be in violation of applicable copyright laws Further you may not modify adapt disassemble decompile translate create derivative works of or in any way reverse engineer the DIGITAL BOOK You may not export or reexport directly or indirectly the DIGITAL BOOK without compliance with appropriate ...

Page 3: ...monstration 9 Selecting Drugs 10 Correcting Misspellings 12 Finding Brands Generics Groups 14 Finding Interactions 16 Between Many Drugs 16 For a Single Drug 18 Viewing References 20 Sending Words to Other Books 22 Digital Book System 23 Limited Warranty 25 Product Specifications 26 Key Guide 27 Index 30 ...

Page 4: ...rug in the group known exceptions to the interaction are noted It is not possible to determine the frequency of most interac tions When an interaction is documented by one or two case reports rather than by clinical studies or reports in many patients the year of each report is given as some indication of frequency Omissions New adverse interactions are continually being reported the absence of a ...

Page 5: ...ds interacting with monoamine oxidase inhibitors are included Mechanisms of Interaction Genetic differences can affect drug metabolism and interactions Drugs can interact by changing the metabolism of other drugs either through inhibition or induction of any of several hepatic enzyme activities or through alterations in hepatic blood flow by altering the binding of other drugs to plasma proteins o...

Page 6: ...drugs drug groups and food groups correct drug name misspellings find foods that interact with MAO inhibitors select up to 20 drugs and view a list of their interactions select a single drug and view a list of the drugs with which it interacts read descriptions and references about drug interactions and look up drugs and words in related digital books Read this User s Manual to learn how ...

Page 7: ...o name Press ENTER SHOW INTERACTIONS Press ENTER You see the interactions if any between the drugs Press ENTER You see a description of the interaction Press CLEAR You re ready to find other interactions Overview of Operation About the Screen Illustrations Some screen illustrations in this User s Manual may vary slightly from what you see on screen These variations do not mean that this digital bo...

Page 8: ...ay be erased 1 Turn the Digital Book System off 2 Install the digital book into a slot on the back of the Digital Book System Align the tabs on the digital book with the notches in the slot Make sure its metal contacts face down 3 Press ON OFF 4 Turn the wheel on the side of the Digital Book System to adjust the screen contrast 5 Press CARD 6 Press or to highlight the HADI icon Installing the Digi...

Page 9: ... Book System at any time When you turn the Digital Book System on again the screen that you last viewed appears Any drugs entered in your query list are saved too Clearing the Main Drug List You can always return to the main drug list by pressing CLEAR Note When you do the drugs in your query list are also cleared You can return to the previous screen without clearing your query list by pressing B...

Page 10: ...Press ENTER to start the demonstration 4 Press CLEAR to stop the demonstration Viewing a Demonstration Help is Always at Hand You can view a help message at any screen except during the demonstration by pressing HELP To read the help message press To exit it press BACK Auto shutoff If you forget to turn this digital book off don t worry It will automatically shut off in four minutes ...

Page 11: ... few letters to highlight an item Try this example 1 Type META at the main drug list To go back a letter press BACK 2 Press ENTER to select the drug and add it to the query list 3 To clear the query press CLEAR Selecting Drugs Drug Selecting Tips You do not need to type capital letters or punc tuation However you can type numbers at the main drug list Note In this User s Manual drug refers to any ...

Page 12: ...roll up and down or Page up and down UP or DN Zoom to the top or or bottom of a list Hold while pressing the other key or press and then the other key The second method flashes a G at the bottom of the screen Follow the Arrows The flashing arrows at the bottom right of the screen indicate which direction keys you can press to move around the screen ...

Page 13: ...cally appears Try this 1 Type KLOROMBUSIL at the main drug list To exit spell correction press BACK repeatedly 2 Press ENTER Spell correction is done automatically 3 Press to highlight a drug if needed 4 Press ENTER to select the drug and add it to your query list 5 To clear the query press CLEAR ...

Page 14: ...EN LBUT ZONE and press ENTER The correct spelling PHENYLBUTAZONE appears Type CORTI To type the asterisk hold SHIFT and press Then press ENTER A list of drug and group names beginning with CORTI appears Note You can type more than one question mark or asterisk in a word and you can type both in the same word However it is not necessary to type two consecutive asterisks in one word Correcting Missp...

Page 15: ...mple we ll find the brand names and drug group of penicillin G 1 Type PENICILLIN G at the main drug list 2 Press SPEC 3 Press repeatedly to view the brands Or hold and press to go to the bottom of the list At the bottom of the list notice that penicillin G belongs to the drug group penicillins 4 Press ENTER to view the drugs in the group Finding Brands Generics Groups ...

Page 16: ...or Interactions When you highlight a food name on the main drug list pressing SPEC shows if that food interacts with MAO inhibitors Try this example 1 Type AVOCADOS 2 Press SPEC MAO Inhibitor info is highlighted 3 Press ENTER A description of avocados and MAO inhibitors appears To read the cross references see Viewing References ...

Page 17: ...action Between Many Drugs You can select up to 20 drugs at time to find interac tions between In this example we ll find the interac tions between alcohol and acetaminophen 1 Select ALCOHOL from the main drug list 2 Then select CAFFEINE You can add more drugs here if you wish 3 Press ENTER to view the interactions Or press MENU and select Query interactions Finding Interactions ...

Page 18: ...t the highlighted interaction This is an interaction description The hand points to a comment or recommendation 6 Press or DN to move down To Press View the drug names of SPEC the interaction description View the next or previous DN or UP description if any Return to the interactions BACK 7 Press CLEAR to clear the queries Finding Interactions ...

Page 19: ...ch it interacts In this example we ll find the interactions for heparin 1 Type HEPARIN at the main drug list 2 Press ENTER 3 Press LIST to view your query list 4 Press or press MENU and select Other interacting items These are the interactions for heparin 5 Press to highlight an interaction 6 Press ENTER to view its description O ...

Page 20: ...ghted item View the interactions between all the items View all the interactions for a highlighted item Go to the main drug list and save your queries Go to main drug list CLEAR and clear your queries Note Your queries are saved between sessions unless you reset the Digital Book System or remove its batteries Note Press BACK to return to the query list each time after selecting one of the above op...

Page 21: ...w its journal reference 1 At an interaction description with a hold and press to highlight the first showing on the screen To highlight the last on the screen hold and press Notice that the is highlighted 2 Press ENTER to view the reference 3 Hold to scroll down Viewing References ...

Page 22: ... Complete Drug Names Pressing or SPEC at an interaction list an interaction description or a reference displays the full names of the drugs involved in the interaction Then press BACK to go back to previous screen Viewing Next or Previous References Once at a reference you can view the next or previous reference if any in an interaction description by holding and pressing UP or DN ...

Page 23: ...t a drug or or item in a list Highlight a word ENTER and then in a description the arrow keys Turn off highlight BACK in a description 2 Hold and press CARD 3 Highlight the icon of the digital book to which you want to send the word 4 Press ENTER To look up the word follow the instructions for that book In many cases you simply press ENTER To return to the Handbook press CARD highlight its icon an...

Page 24: ...n resetting the Digital Book System If nothing happens then reset Protecting and Cleaning Do not touch the metal contacts on the back of digital books or the rubber contacts on the Digital Book Sys tem with statically charged objects Statically charged objects may erase information that you entered in the digital books Do not put excessive weight on digital books or the Digital Book System or expo...

Page 25: ...new batteries in the cavities with the s oriented correctly In the DBS 1 and DBS 2 the s should face up 6 Replace the battery cover Battery Precautions When you replace batteries follow these precau tions to avoid erasing information on your in stalled digital books Replace the batteries before they lose power Once batteries have been removed install new ones within two minutes Do not mix old and ...

Page 26: ...ION OR EXTENSION OF THIS EXPRESS WARRANTY THEFOREGOINGWARRANTYISEXCLUSIVEANDISINLIEUOFALLOTHEREXPRESS OR IMPLIED WARRANTIES WRITTEN OR ORAL INCLUDING BUT NOT LIMITED TO WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE YOUR SOLE AND EXCLUSIVE REMEDY SHALL BE FRANKLIN S OBLIGATION TO REPLACE OR REFUND AS SET FORTH ABOVE IN THIS WARRANTY Some States do not allow the exclusion of impl...

Page 27: ...ight 0 3 oz Copyrights Trademarks Patents ISBN 1995 97 Franklin Electronic Publishers Inc Burlington NJ 08016 4907 USA All rights reserved 1997 by the Medical Letter Inc All rights reserved MatchMaker is a trademark of Franklin Electronic Publishers Inc The Medical Letter is a registered trademark of the Medical Letter Inc U S Patent 4 490 811 4 830 618 5 113 340 5 218 536 5 396 606 DES 348 439 DE...

Page 28: ... generics and groups Exits the digital book Gold Key Combinations Types numbers Sends a word to another book or Zooms to the start or end of a list section description or reference DN or UP Shows the next or previous description or reference or Highlights a reference mark in a description Key Guide MORE CLEAR GAMES LIST MENU SPEC CARD CARD Q P ...

Page 29: ...he full menu item at the main drug list types a to stand for an unknown letter At the main drug list types an to find a series of letters in a word Query List Keys These functions apply only when in the query list Shows the main drug list Deletes a highlighted item Shows interactions for a highlighted item Shows the interactions between all the items D Q A O SHIFT UP DN ...

Page 30: ...letes an entry or turns off the highlight in interaction descriptions Enters a request In descriptions highlights a word Shows a help message Turns unit on or off Types punctuation Shifts keys Types a space BACK A Key Guide ENTER ON OFF HELP Z SPACE SHIFT ...

Page 31: ...s installing 7 Direction keys 11 Drug groups 14 Drug names correcting spellings 12 entering 10 Drugs brand generic 14 correcting spellings 12 displaying full names 21 entering 10 finding 14 finding spellings 13 selecting 10 Finding adverse interactions between many drugs 16 for a single drug 18 brand names 14 comments recommenda tions 17 drug groups 14 food groups 10 generics 14 help messages 9 in...

Page 32: ...to 8 using 10 14 MAO inhibitor interac tions 15 MatchMaker key 13 28 Misspellings correct ing 12 Product specifications 26 Query list deleting a drug 19 recommendations 17 seeing interactions from 19 using the query list 19 References viewing 20 viewing the next or previous 21 Resuming sessions 8 Sending words between books 22 SPEC key 14 SPEC key using 17 Spellings correcting 12 finding 13 Warran...

Page 33: ...32 FCR 28508 00 P N 7201747 Rev A ...

Page 34: ...FOLD User s Manual HANDBOOK OF ADVERSE DRUG INTERACTIONS Rx The Medical Letter DIGITAL BOOK F IC 168 Electronic Publishers For Use with the Franklin Digital Book System Electronic Publishers ...

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