December 11, 2015, WAT051512 Rev. B
Page 1
Waters Gradient Mixer
The Waters
®
Gradient Mixer (kit part number WAT051518) is a stainless steel mixing
chamber for multi-component mobile phase applications where the gradient is
generated within the system and a homogeneous solvent blend is critical. The module
blends solvents from either separate gradient or on-line isocratic solvent delivery
systems at flow rates between 1.0 and 9.9 milliliters per minute. The mixer provides
significant chromatographic improvement in compositional consistency, resulting in
reduced baseline noise at high detector sensitivity.
Note:
For safety advisory information, see the Safety Appendix in the associated
operator’s guide.
Introduction
Generally, the greater the imbalance between the solvents used to make up the
mobile phase, the more mixing volume is required. The Gradient Mixer enhances
mixing through a series of cascaded low-volume mixing chambers. The chambers,
connected by 0.005-inch channels, cause linear velocity to increase as solvent flows
through them. Wetted surfaces are 316 stainless steel and TFE Teflon seals. The
Gradient Mixer is compatible with any backpressure within the normal operating range
of standard Waters solvent delivery systems.
Contents:
Topic
Page
Introduction ................................................................................................ 1
Required materials ....................................................................................... 2
Operating the gradient mixer......................................................................... 3
Maintaining the gradient mixer ...................................................................... 4
Waters and “THE SCIENCE OF WHAT’S POSSIBLE.” are
registered trademarks of Waters Corporation.
All other trademarks are the sole property of their respective owners.
Copyright © 1991
−
2015 Waters Corporation.
*WAT051512*
*Rev.B*
